Before any laser treatment of pigmented lesions, any lesion with atypical features should be biopsied to rule out malignancy. The treatment of congenital melanocytic naevi is a controversial issue. The long-term effect of using lasers on promoting melanoma is not known, but the treatment is thought to be low risk.

The stan­dard f‑number scale is: 1, 1.4, 2, 2.8, 4, 5.6, 8, 11, 16, 22, 32, and so on. The dif­fer­ence in expo­sure between adja­cent num­bers is one stop, which means that it either dou­bles or halves the amount of light pass­ing through the lens depend­ing on whether you’re open­ing or clos­ing the aper­ture. How­ev­er, the numer­ic sequence grows by a fac­tor of about 1.4 or shrinks by a fac­tor of about 0.7.

Let’s pre­tend we have two lens­es attached to iden­ti­cal cam­eras: one lens is 50 mm and the oth­er is 100 mm, and both have entrance pupils with 25 mm diam­e­ters. Since their entrance pupils are iden­ti­cal in size, an equal amount of light enters each lens. How­ev­er, because the focal length of the 100 mm lens is twice that of the 50 mm lens, the light pass­ing through it has to trav­el twice the dis­tance to reach its camera’s image sen­sor, which pro­duces a dark­er image.

Recently non-ablative lasers have been used for dermal modelling; 'non-ablative' refers to heating the dermal collagen while avoiding damage to the surface skin cells (epidermis) by cooling it. Multiple treatments are required to smooth the skin.

IMPORTANT NOTICE: DermNet does not provide a free online consultation service. If you have any concerns with your skin or its treatment, see a dermatologist for advice.

F-stop

Vascular skin lesions contain oxygenated haemoglobin, which strongly absorbs visible light at 418, 542 and 577 nm, whereas pigmented skin lesions contain melanin, which has a broad range of absorption in the visible and infrared wavebands. Infrared lasers are broadly destructive because they are absorbed by water in and between skin cells (these are composed of 70-90% water).

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Aperture

The QS laser systems can selectively destroy the tattoo pigment without causing much damage to the surrounding skin. The modified pigment is removed from the skin by scavenging white blood cells, tissue macrophages. The choice of laser depends on the colour, depth and chemical nature of the tattoo ink. Two to ten treatments are often necessary. Yellow, orange and green are the most difficult colours to remove.

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f-number

Hi there, my name is Paul, and this is Expo­sure Ther­a­py. In this video, I’ll explain the rea­son for the inverse numer­i­cal rela­tion­ship between f‑numbers and the aper­ture. This rela­tion­ship is a wide­spread point of con­fu­sion for many begin­ner pho­tog­ra­phers, who regard it as irra­tional or need­less­ly com­plex. My goal is to dis­pel the mys­tery around f‑numbers and demon­strate why they’re a per­fect­ly rea­son­able method for express­ing how the aper­ture affects expo­sure.

Chang­ing the size of the aper­ture adjusts the inten­si­ty of light pass­ing through the lens. Increas­ing the aperture’s size allows more light to pass through the lens, increas­ing expo­sure and cre­at­ing a brighter pic­ture. Con­verse­ly, decreas­ing the aperture’s size reduces how much light pass­es through the lens, reduc­ing expo­sure and result­ing in a dark­er pho­to.

Note to our readers. This page is overdue for an update; there have been significant changes in laser technology since it was originally written.

I hope this helped you under­stand the inverse numer­i­cal rela­tion­ship between f‑numbers and their effect on the aper­ture. If you have requests for future top­ics, let me know in the com­ments, and I’ll address them in future videos. In the mean­time, you can learn more about pho­tog­ra­phy on ExposureTherapy.ca. See you next time.

f-stop vsaperture

aperture中文

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These equa­tions demon­strate that choos­ing the same f‑number on a lens of any focal length will result in the same amount of light pass­ing through the lens. They also explain the inverse rela­tion­ship between f‑numbers and expo­sure. For a giv­en focal length, as the aperture’s size increas­es, the ratio decreas­es, and vice ver­sa.

Last­ly, dou­bling the f‑number, such as chang­ing it from ƒ/2.8 to ƒ/5.6, reduces pic­ture bright­ness by one-quar­ter. And con­verse­ly, halv­ing the f‑number, such as adjust­ing from ƒ/8 to ƒ/4, increas­es pic­ture bright­ness four times.

The new V-beam features provide ultra-long pulse duration so energy directed at the target blood vessels over a longer period, resulting in more uniform blood vessel damage reducing the purpura seen with the earlier pulse dye lasers. The addition of dynamic cooling increases comfort during treatment enabling higher fluencies (energy) to be delivered safely and effectively, so fewer treatments are required.

F-stops

Under­stand­ing the rela­tion­ship between pic­ture bright­ness and both the shut­ter speed and ISO is straight­for­ward for stu­dents learn­ing the basics of pho­tog­ra­phy. Shut­ter speed is expressed numer­i­cal­ly in time units, with the most com­mon being frac­tions of a sec­ond; longer dura­tions result in brighter pic­tures, and short­er dura­tions result in dark­er pic­tures. ISO is also expressed numer­i­cal­ly; big­ger num­bers pro­duce brighter pho­tos, and small­er num­bers make dark­er pho­tos.

The wavelength peaks of the laser light, pulse durations and how the target skin tissue absorbs this, determine the clinical applications of the laser types.

Melanin-specific, high energy, QS laser systems can successfully lighten or eradicate a variety of pigmented lesions. Pigmented lesions that are treatable include freckles and birthmarks including some congenital melanocytic naevi, blue naevi, naevi of Ota/Ito and Becker naevi. The short pulse laser systems effectively treat the lesions by confining their energy to the melanosomes, which are the tiny granules containing melanin inside the pigment cells. The results of laser treatment depend on the depth of the melanin and the colour of the lesion and are to some degree unpredictable. Superficially located pigment is best treated with shorter wavelength lasers while removal of deeper pigment requires longer wavelength lasers that penetrate to greater tissue depths. Caution is needed with laser therapy in skin of colour, as permanent hypopigmentation and depigmentation may occur. Successfully treated lesions may recur.

f-stop是什么

Pulsed CO2 and erbium:YAG lasers have been successful in reducing and removing facial wrinkles, acne scars and sun-damaged skin. High-energy, pulsed, and scanned CO2 laser is generally considered the gold standard against which all other facial rejuvenation systems are compared. Typically a 50% improvement is found in patients receiving CO2 laser treatment. Side effects of treatment include post-operative tenderness, redness, swelling and scarring. The redness and tenderness last several weeks, while new skin grows over the area where the damaged skin has been removed by the laser treatments (ablative laser systems). Secondary skin infection including reactivation of herpes is also a potential problem until healing occurs. Extreme caution is needed when treating darker-skinned individuals as a permanent loss, or variable pigmentation may occur longterm.

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The first lasers used to treat skin conditions occurred over 40 years ago. Argon and carbon dioxide (CO2) lasers were commonly used to treat benign vascular birthmarks such as port-wine stains and haemangiomas. Although these birthmarks could be effectively lightened, a side effect was the unacceptably high rate of scar formation. In the last 20 years, advances in laser technology have revolutionised their use in the treatment of many skin conditions and congenital defects, including vascular and pigmented lesions, and the removal of tattoos, scars and wrinkles. There is a spectrum of laser and light technologies available for skin resurfacing and rejuvenation.

Treatment with quasi-CW lasers also produce effective outcomes, but they may be associated with higher incidences of scarring and textural changes. The most common side effects include mild erythema, oedema, and transient crusting.

A 50 mm lens set to ƒ/4 will have an entrance pupil diam­e­ter of 12.5 mm—because 50 divid­ed by 12.5 equals 4. A 24 mm lens set to ƒ/8 will have an entrance pupil diam­e­ter of 3 mm. Some lens­es can open to ƒ1.0, in which case the entrance pupil diam­e­ter and focal length are equal.

Lasers are sometimes used to remove viral warts by vaporisation (CO2 laser) or destruction of the dermal blood vessels (PDL), but the evidence would suggest that this is no more effective than standard wart paints or even waiting for spontaneous clearance.

Keloids and hypertrophic scars are difficult to eradicate, and traditional treatments are not always successful. Vaporising lasers (CO2 and erbium:YAG) have been useful as an alternative to conventional surgery. More recently PDL has been used to improve hypertrophic scars and keloids. This may require multiple treatment sessions or the simultaneous use of intralesional injections to gain good results. The PDL has been reported to reduce the redness as well as improving the texture and flexibility of the scar.

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Vascular malformations associated with smaller more superficial blood vessels respond better to treatment than deeper larger vessels (more often arising in older individuals). It is, therefore, best to begin treatment early. Fading by 80% occurs after 8 to 10 treatments on average. Further treatment may be necessary if the lesion recurs.

The pulsed dye laser is considered the laser of choice for most vascular lesions because of its superior clinical efficacy and low-risk profile. It has a large spot size (5 to 10mm) allowing large lesions to be treated quickly. Side effects include postoperative bruising (purpura) that may last 1-2 weeks and transient pigmentary changes. Crusting, textural changes and scarring are rarely seen.

The CO2 laser can be used to remove a variety of skin lesions including seborrhoeic keratoses and skin cancers by vaporisation or in cutting mode. However, conventional surgery or electrosurgery can also be used and is generally less expensive.

Lasers can be used to remove excessive and cosmetically disabling hair due to hypertrichosis or hirsutism. Laser treatments remove dark hair quickly, and it may take 3 to 6 months before regrowth is evident. Several treatment cycles are required with the spacing between treatments depends on the body area being treated. Laser treatments are less painful and much quicker than electrolysis. Complications are rare but superficial burns, pigmentary changes and even scarring may occur. Increased growth of fine dark hair in untreated areas close to the treated ones has been reported. Both increased and reduced localised sweating have been reported after treatment.

When you hold a lens up and look at the aper­ture, what you’re see­ing is tech­ni­cal­ly called the “entrance pupil.” The entrance pupil is the opti­cal image of the phys­i­cal aper­ture as seen through the front of the lens. This dis­tinc­tion mat­ters because when you look at the front of a lens, you see the aper­ture through mul­ti­ple lay­ers of glass that affect its mag­ni­fi­ca­tion and per­ceived loca­tion in space com­pared to the phys­i­cal open­ing in the iris. For the sake of sim­plic­i­ty, I’ll use “aper­ture” when refer­ring to both the set­ting and the phys­i­cal open­ing and “entrance pupil” in ref­er­ence to dimen­sions.

Erbium:YAG produces similar results and side effects to the CO2 laser. Despite their side effect profile and long recovery time these ablative laser systems, when used properly, can produce excellent results.

This is pre­cise­ly why the f‑number is some­times called the f‑ratio. The f‑number express­es a ratio of the lens focal length to the diam­e­ter of the entrance pupil, and it’s defined by the equa­tion N=ƒ/D. Thus, the f‑number equals the focal length divid­ed by the entrance pupil diam­e­ter. It can also be mod­i­fied to solve for the entrance pupil diam­e­ter using the equa­tion D=ƒ/N. Thus, the entrance pupil diam­e­ter equals the focal length divid­ed by the f‑number.

The best way to address this is by start­ing with the basics. Inside every inter­change­able lens is a ring of over­lap­ping blades col­lec­tive­ly known as an iris diaphragm or iris. Expand­ing or con­tract­ing the blades adjusts the open­ing in the cen­tre of the iris, called the aper­ture.

The 100 mm lens can pro­vide an expo­sure equal to its 50 mm coun­ter­part by open­ing its aper­ture to col­lect four times more light, assum­ing its aper­ture can open that much. Since aper­tures are rough­ly cir­cu­lar, we can deter­mine how big they should be by cal­cu­lat­ing the area of a cir­cle. An entrance pupil with a 25 mm diam­e­ter has an area of about 491 mm^2. The 100 mm lens would need an entrance pupil with an area of 1,964 mm^2, which is formed by a cir­cle with a 50 mm diam­e­ter. Sim­ple, right?

Unfor­tu­nate­ly, the rela­tion­ship between f‑numbers, aper­ture size, and pic­ture bright­ness is not as imme­di­ate­ly intu­itive. Begin­ners are con­fused by the neg­a­tive (or inverse) rela­tion­ship between f‑numbers and aper­ture size. In addi­tion, they have a hard time under­stand­ing why big­ger f‑numbers rep­re­sent small­er aper­tures that reduce bright­ness, and small­er f‑numbers define larg­er aper­tures that increase bright­ness.

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Pupilaperture

Pulsed* lasers emit high-energy laser light in ultrashort pulse durations with relatively long intervening periods between each pulse

Reduc­tion in bright­ness occurs because light has the prop­er­ty of spread­ing out as it recedes from its source, and from the per­spec­tive of your camera’s image sen­sor, this source is the point inside the lens from which focal length is mea­sured. This trait of light to dif­fuse out­wards is described by the Inverse Square Law, which states that inten­si­ty is inverse­ly pro­por­tion­al to the square of the dis­tance. In this exam­ple, the inverse square law informs us that the 100 mm lens expos­es its camera’s image sen­sor to 1/4 the light com­pared to the 50 mm lens because it’s twice as long. This occurs because one over two squared equals one-quar­ter.

The aim is to destroy the target cells and not to harm the surrounding tissue. Short pulses reduce the amount that the damaged cells heat, thereby reducing thermal injury that could result in scarring. Automated scanners aim to reduce the chance of overlapping treatment areas.

Lasers have been used successfully to treat a variety of vascular lesions including superficial vascular malformations (port-wine stains), facial telangiectases, haemangiomas, pyogenic granulomas, Kaposi sarcoma and poikiloderma of Civatte. Lasers that have been used to treat these conditions include argon, APTD, KTP, krypton, copper vapour, copper bromide, pulsed dye lasers and Nd:YAG. Argon (CW) causes a high degree of non-specific thermal injury and scarring and is now largely replaced by yellow-light quasi-CW and pulsed laser therapies.

For­tu­nate­ly, pho­tog­ra­phers don’t need to per­form such cal­cu­la­tions to take pic­tures! That’s because hid­den with­in these num­bers is a straight­for­ward rela­tion­ship. For exam­ple, notice how the expo­sure pro­duced by the 50 mm lens with a 25 mm entrance pupil is iden­ti­cal to the 100 mm lens with a 50 mm entrance pupil. This is because in both cas­es, the ratio of the focal length to the entrance pupil diam­e­ter is 2:1.

The Excimer laser uses noble gas and halogen to produce ultraviolet radiation (308 nm) that will clear psoriasis plaques. However, the small spot size and the tendency to cause blistering makes treatment time-consuming and difficult to perform.

Suitable devices include long-pulsed ruby and alexandrite lasers, a diode (810nm), millisecond Nd:YAG and non-laser intense pulsed light.

Violet-blue metal halide light (407-420 nm) has been used to treat acne because it has a toxic effect on the acne bacteria, Cutibacterium acnes.

*Pulsed laser systems may be either long-pulsed such as PDL with pulse durations ranging from 450ms to 40millisec, or very short-pulsed (5-100ns) such as the quality-switched (QS) lasers.

We express aper­ture val­ues using f‑numbers and not as the mea­sured size of the entrance pupil, such as its diam­e­ter, radius, or area, because it neglects the essen­tial role of focal length. This can be demon­strat­ed with a thought exer­cise.

There are several types of lasers used in skin laser surgery. Older laser technologies such as the continuous wave (CW) lasers of CO2 and argon have been replaced with quasi-CW mode lasers and pulsed laser systems. Picosecond lasers have very short pulses.

Most pho­tog­ra­phers sim­ply com­mit the stan­dard f‑number scale to mem­o­ry. How­ev­er, if you’re hav­ing trou­ble, a more straight­for­ward method is to remem­ber just the first two numbers—1 and 1.4—because the rest of the scale is an iter­a­tion of dou­bling each in alter­nat­ing order. The next f‑number is always dou­ble the pre­vi­ous one. So the num­ber after ƒ/1.4 is dou­ble of ƒ/1, which is ƒ2. Like­wise, the num­ber after ƒ/2 is dou­ble of ƒ/1.4, which is ƒ/2.8.  And on and on it goes.

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The light is produced within an optical cavity containing a medium, which may be a gas (eg, argon, krypton, carbon dioxide), liquid (eg, dye) or solid (eg, ruby, neodymium:yttrium-aluminium-garnet, alexandrite). The process involves excitation of the molecules of the laser medium, which results in the release of a photon of light as it returns to a stable state. Each medium produces a specific wavelength of light, which may be within the visible spectrum (violet 400 through to red 700nm) or infrared spectrum (more than 700 nm).

In both cas­es, the rela­tion­ship between the set­ting and its effect on pic­ture bright­ness is easy to under­stand because there’s a pos­i­tive cor­re­la­tion, and they move in tan­dem. For exam­ple, when you dou­ble the expo­sure dura­tion, it dou­bles the bright­ness; when you halve the ISO, it halves the bright­ness. It’s a sim­ple rela­tion­ship that stu­dents in my pho­tog­ra­phy work­shops grasp with ease.