Monophasic form, which involves a single attack that lasts a month or 2 then may be free from attacks for several years. Men and women get this type equally.

A process called plasmapheresis, also known as plasma exchange, which removes harmful antibodies from the blood that may be playing a role in the condition

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Experts don't consider this condition curable. But your healthcare provider can prescribe medicines or other treatments to reduce the effects of the disease and relieve symptoms. These may include:

The onset of NMO varies from childhood to adulthood, with two peaks, one in childhood and the other in adults in their 40s. Women are more often affected than men.

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Experts used to think that NMO was a type of multiple sclerosis. They now think it may be a different condition. The conditions do have some similar symptoms, however they are usually more severe in NMO. Vision problems with multiple sclerosis usually affect 1 eye at a time, while NMO may affect both eyes at the same time.

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Neuromyelitis optica (NMO) is a rare autoimmune disease that affects the central nervous system. It's also called neuromyelitis optica spectrum disorder (NMOSD) or Devic's disease. NMO specifically affects the myelin, which is the insulation around the nerves. NMO mainly affects the spinal cord and the optic nerves—the nerves that carry signals from the eyes to the brain. As a result, the disease can cause paralysis and blindness.

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NMO is a rare but serious disease that affects the central nervous system. NMO mainly affects the spinal cord and optic nerves.

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With NMO, your immune system attacks a substance in your body called myelin—the insulation around your nerves. Specifically, the myelin cells in the spinal cord and optic nerves are attacked. Usually, people with NMO have flare-ups of the disease that may strike months or years apart. Between these flare-ups, people may have some recovery.

Respiratory viruses continue to circulate in Maryland, so masking remains strongly recommended when you visit Johns Hopkins Medicine clinical locations in Maryland. To protect your loved one, please do not visit if you are sick or have a COVID-19 positive test result. Get more resources on masking and COVID-19 precautions.

Disability from NMO may become worse over time. Most people with NMO develop weakness in their arms and legs. Others may have more severe symptoms. Some people with NMO need to start using a ventilator. This is a machine that helps them breathe. They may also need to work with an occupational therapist or social worker to address their disabilities.

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At the visit, write down the name of a new diagnosis and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you.

Many healthcare providers, including physical and occupational therapists and social workers, can help you deal with your disease.

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Relapsing form, which has periodic flare-ups, with some recovery in between. This is the more common kind. Women are far more likely to have this form than men.

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Like many medical facilities across the nation, our supply chain is feeling the effects of Hurricane Helene’s aftermath. Johns Hopkins Medicine currently has a sufficient sterile fluid supply to meet treatment, surgical and emergency needs. However, we have put proactive conservation measures into place to ensure normal operations, always with patient safety as our first priority. Examples of sterile fluids include intravenous (IV), irrigation and dialysis fluids. Learn more.

If you or a family member is diagnosed with NMO, it is important to build a support system that includes family, friends, professionals, and support groups. A person with major disabilities may need the support of neurologists who specialize in NMO, occupational therapists, physical therapists, and social services professionals.