6 of the Most Flammable Household Items - USA Fire Protection - flammable

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Vomiting, abdominal pain, diarrhea, tremors, seizures, colic, hypertension, cardiac arrest, dyspnea and cyanosis, ventricular fibrillation, severe hypokalemia, skeletal muscle weakness

Nausea, vomiting, rash (may be acneiform), slurred speech, ataxia, confusion, psychotic behavior, coma, paralysis, negative anion gap

Nausea, vomiting, diarrhea, hemorrhagic gastroenteritis, weakness, lethargy, CNS depression, seizures, “boiled lobster” rash, shock

If a term is not readily visible in the alphabetical listing of poisons, try searching the current web page according to the conventions of your device and browser.

For single ingestion, observationVitamin K Toxicity) until INR is normal, transfusion with fresh frozen plasma if necessary

Abdominal pain (colic), vomiting (may be bloody), diarrhea (may be bloody), stomatitis, excessive salivation, tremors, leg pains, paresthesias, polyneuritis, ocular and facial palsy, delirium, seizures, respiratory failure, loss of hair about 3 weeks after poisoning

If usual 6% household preparations have been ingested, dilution with milk (little else required)If concentrated forms have been ingested, esophagoscopy, treatment of shock

Acute ingestion: Thirst, burning abdominal pain, vomiting, diarrhea; CNS symptoms (eg, irritability, inattentiveness, decreased level of consciousness, seizures)Acute inhalation: Insomnia, headache, ataxia, mania, seizuresChronic exposure: Anemia, peripheral neuropathy, confusion, lead encephalopathy, acceleration of atherosclerosis

Increased activity, exhilaration, talkativeness, insomnia, irritability, exaggerated reflexes, anorexia, diaphoresis, tachyarrhythmia, anginal chest pain, psychotic-like states, inability to concentrate or sit still, paranoia

Stimulation then depression, nausea, vomiting, loss of self-control, anxiety, hallucinations, sweating, hyperthermia, seizures, MI (rare)

Ingestion: Blood transfusion for severe hemolysis, urine alkalinization for hemoglobinuria, benzodiazepines to control seizuresSkin contact: Clothing removed if formerly stored with naphthalene moth balls, flushing of skin and eyes

Ingestion: Irritation, corrosion of mouth and GI tract, possible ulceration or perforation, abdominal pain, tachycardia, prostration, circulatory collapseInhalation: Severe respiratory and ocular irritation, glottal spasm, cough, choking, vomiting, pulmonary edema, cyanosis

Corrosive effects, mucous membrane burns, pallor, weakness, shock, seizures in children, pulmonary edema, smoky urine, esophageal stricture (rare)

Excitement, confusion, muscular twitching, weakness, abdominal cramps, generalized myoclonus, CNS depression, rapid respirations, palpitations, cardiovascular collapse, coma, respiratory failure

Bitter almond odor (suggests cyanides), drowsiness, headache, vomiting, ataxia, nystagmus, brown urine, convulsive movements, delirium, cyanosis, coma, respiratory arrest

Inhalation: Intense eye and nasal irritation, headache, dyspnea, sense of suffocation, glottal edema, pulmonary edema, bronchitis, pneumonia, mediastinal and subcutaneous emphysema due to bleb rupture

Ingestion: Irritation, corrosion of mouth and GI tract, possible ulceration or perforation, abdominal pain, tachycardia, prostration, circulatory collapse

Cyanosis due to formation of methemoglobin and sulfhemoglobin, dyspnea, weakness, vertigo, angina, rashes and urticaria, vomiting, delirium, depression, respiratory and circulatory failure

Pyrethrin, and pyrethroidsBifenthrinCyfluthrinCypermethrinEsfenvalerateFluvalinateLambda-cyhalothrinPyrethrinResmethrinSumithrinTefluthrinTetramethrin

See specific gas, eg, Ammonia gas, Carbon monoxide , Chlorine (tear gas), Hydrogen sulfide (sewer gas, volatile hydrides), and Organophosphates (nerve gas)

Protection of patient and attendant from vomitus and fecesFor phosphorus embedded in skin:Submersion of the patient’s body in waterIrrigation with dilute K permanganate or cupric sulfate (250 mg in 250 mL of water), recommended by some expertsPrevention of shockMeticulous surgical debridement

Vomiting, abdominal pain, diarrhea, tremors, seizures, colic, hypertension, cardiac arrest, dyspnea and cyanosis, ventricular fibrillation, severe hypokalemia, skeletal muscle weakness

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Slightly toxic effects (eg, with methoxychlor) to highly toxic effects (eg, with dieldrin)Vomiting (early or delayed), paresthesias, malaise, coarse tremors, seizures, pulmonary edema, ventricular fibrillation, respiratory failure

Petroleum distillates (see Hydrocarbon Poisoning)AsphaltBenzine (benzin)Fuel oilGasolineKeroseneLubricating oilsMineral spiritsModel airplane glueNaphthaPetroleum etherTar

Throat constriction, dysphagia, burning GI pain, vomiting, diarrhea, GI hemorrhage, dehydration, pulmonary edema, renal failure, lactic acidosis, liver failure, shock

Vapor inhalation, skin absorption, or ingestion: CNS symptoms (eg, insomnia, restlessness, ataxia, delusions, mania, seizures)

For diagnostic or therapeutic trial or for treatment of severe symptoms refractory to sedation, which is rarely needed (CAUTION:

Ingestion: Observation for kidney and liver damage; respiratory, cardiac, and circulatory supportInhalation: Respiratory, cardiac, and circulatory support

Vomiting (early or delayed), paresthesias, malaise, coarse tremors, seizures, pulmonary edema, ventricular fibrillation, respiratory failure

Corrosive effects, mucous membrane burns, pallor, weakness, shock, seizures in children, pulmonary edema, smoky urine, esophageal stricture (rare)Respiratory, cardiac, and circulatory failure

Andexanet alfa competitively binds to the Xa inhibitor:Low-dose andexanet alpha: Initial IV bolus of 400 mg at 30 mg/min followed by 4 mg/min for up to 120 minutesHigh-dose andexanet alpha: Initial IV bolus of 800 mg at a rate of 30 mg/min followed by 8 mg/min for up to 120 minutes

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Anticholinergic effects (eg, blurred vision, urinary hesitation), CNS effects (eg, drowsiness, stupor, coma, ataxia, restlessness, agitation, hyperactive reflexes, muscle rigidity, seizures), cardiovascular effects (eg, tachycardia, other arrhythmias, bundle branch block, QRS widening, impaired conduction, heart failure), respiratory depression, hypotension, shock, vomiting, hyperpyrexia, mydriasis, diaphoresis

Ingestion: Inebriation but no alcohol odor on breath, nausea, vomitingLater, carpopedal spasm, lumbar pain, oxalate crystalluria, oliguria progressing to anuria and acute renal failure, respiratory distress, seizures, comaEye contact: Iridocyclitis

Lethargy, nystagmus, pinpoint pupils, tachycardia, coma, respiratory depression (NOTE: Toxicity may be delayed up to 12 hours.)

Ingestion:Skin contact: Clothing removed and area washed with copious soap and water; then as for inhalationInhalation: Oxygen, respiratory support, blood transfusion

Vomiting, upper abdominal pain, pallor, cyanosis, diarrhea, drowsiness, shock; possible toxicity if > 20 mg/kg of elemental iron is ingested

Throat constriction, dysphagia, burning GI pain, vomiting, diarrhea, GI hemorrhage, dehydration, pulmonary edema, renal failure, lactic acidosis, liver failure, shock

100% Oxygen by mask, respiratory support if needed, immediate measurement of carboxyhemoglobin level; if carboxyhemoglobin is more than about 25%, consideration of hyperbaric oxygen in consultation with poison control center (see Carbon Monoxide Poisoning)

OrganophosphatesAcephateBidrinChlorethoxyfosChlorothionChlorpyrifosCoumaphosDemetonDiazinonDichlorvosDimethoateDisulfotonEthionFamphurFenthionHexaethyltetraphosphateIsofenphosLeptophosMerphosMethidathionMethyl parathionMipafoxNaledNerve gas agentsOctamethyl pyrophosphoramideOxydemeton-methylParathionPhoratePhosdrinPhosmetPirimiphos-methylTemefosTerbufosTetrachlorvinphosTrichlorfonTriorthocresyl phosphate

Anticholinergic symptoms (eg, tachycardia, hyperthermia, mydriasis, warm and dry skin, urinary retention, ileus, delirium)

Vapor inhalation, skin absorption, or ingestion: CNS symptoms (eg, insomnia, restlessness, ataxia, delusions, mania, seizures)

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Bitter almond odor (suggests cyanides), drowsiness, headache, vomiting, ataxia, nystagmus, brown urine, convulsive movements, delirium, cyanosis, coma, respiratory arrest

Slightly to highly toxic effects; similar to those of organophosphates except cholinesterase inhibition is not permanentSee Organophosphates

Acute: Abdominal pain, oliguria, acute renal failureChronic: Poor absorption, ulcerative stomatitis, anorexia, progressive encephalopathy

Vapor inhalation: Euphoria, burning in chest, headache, nausea, weakness, CNS depression, confusion, dyspnea, tachypnea, rales, possibly myocardial sensitization to catecholamines (which can result in cardiac arrhythmias)

Acute: Severe gastroenteritis, burning mouth pain, salivation, abdominal pain, vomiting, colitis, nephrosis, anuria, uremia

See specific agentChlorinated and other halogenated hydrocarbons, Organophosphates, Paradichlorobenzene, and Pyrethroids

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Dizziness, incoordination, stupor to coma, gastroenteritis, hemorrhagic gastritis, hypotensionKetosis without acidosisNo retinal injury or acidosis

Nausea, vomiting, rash (may be acneiform), slurred speech, ataxia, confusion, psychotic behavior, coma, paralysis, negative anion gap

Throat constriction, dysphagia, burning GI pain, vomiting, diarrhea, GI hemorrhage, dehydration, pulmonary edema, renal failure, lactic acidosis, liver failure, shock

Milk, starch, or flour po; early airway support; fluid and electrolytes; treatment of shock; early, aggressive airway management

Ingestion: Burning throat and stomach, vomiting, diarrhea, pneumonia only if aspiration has occurredVapor inhalation: Euphoria, burning in chest, headache, nausea, weakness, CNS depression, confusion, dyspnea, tachypnea, rales, possibly myocardial sensitization to catecholamines (which can result in cardiac arrhythmias)Aspiration: Early acute pulmonary changes

See specific acids and alkalis (eg, , Fluorides) and Caustic IngestionEye contact: See Overview of Eye TraumaSkin contact: See Burns

Mercury, compounds ofAmmoniated mercuryBichloride of mercuryCalomelCorrosive sublimateDiuretics, mercurialMercuric chloride (corrosive sublimate)Merthiolate

Corrosive effects due to oxidation, ulcerated and perforated nasal septum, severe gastroenteritis, shock, vertigo, coma, nephritis

Methemoglobinemia, cyanosis, anoxia, GI disturbance, vomiting, headache, dizziness, hypotension, respiratory failure, coma

Hypertension, tachycardia, MI, nausea, vomiting, agitation, hallucinations, psychoses, seizures, convulsions, strokeSee also Cannabinoids, synthetic

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Thirst, diarrhea, vomiting, light-headedness, burning feet, increased heart rate and BP, cardiovascular collapse, seizures, hypotension, coma, abortion, gangrene of feet, cataracts

Air contaminants that form atmospheric oxidants and that have been liberated from missile fuels, explosives, or agricultural wastes

For diagnostic or therapeutic trial or for treatment of severe symptoms refractory to sedation, which is rarely needed (CAUTION:

Irritated skin and mucous membranes, skin vesicles, nausea, vomiting, bloody diarrhea, burning pain in back and urethra, respiratory depression, seizures, coma, abortion, menorrhagia

Headache, weakness, leg cramps, vertigo, seizures, retinal injury, dimmed vision, metabolic acidosis, decreased respiration

Irritability, CNS excitation, muscle spasms, atonia, tonic-clonic seizures, respiratory failure, pulmonary edema, nausea, vomiting, obtundation, coma

Absorption via skin, inhalation, or ingestion: Nausea, vomiting, abdominal cramping, excessive salivation, increased pulmonary secretion, headache, rhinorrhea, blurred vision, miosis, slurred speech, mental confusion, difficulty breathing, frothing at the mouth, coma

Ingestion: Abdominal cramps, nausea, vomiting, headache, confusion, dysuria, intravascular hemolysis, seizures, hemolytic anemia in people with G6PD deficiencySkin contact: Dermatitis, corneal ulcerationInhalation: Headache, confusion, vomiting, dyspnea

Throat constriction, dysphagia, burning GI pain, vomiting, diarrhea, GI hemorrhage, dehydration, pulmonary edema, renal failure, lactic acidosis, liver failure, shock

See specific components (eg, Barium compounds, Fluorides, Phosphorus [yellow or white], Thallium salts, Anticoagulants, warfarins)

Vomiting, upper abdominal pain, pallor, cyanosis, diarrhea, drowsiness, shock; possible toxicity if > 20 mg/kg of elemental iron is ingested

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Ingestion of small or moderate doses: Salty or soapy tasteIngestion of large doses: Tremors, seizures, CNS depression, shock, renal failureSkin and mucosal contact: Painful superficial or deep burnsInhalation: Intense eye and nasal irritation, headache, dyspnea, sense of suffocation, glottal edema, pulmonary edema, bronchitis, pneumonia, mediastinal and subcutaneous emphysema due to bleb rupture

Corrosive effects due to oxidation, ulcerated and perforated nasal septum, severe gastroenteritis, shock, vertigo, coma, nephritis

Allergic response (including anaphylactic reactions and skin sensitivity) in sensitive people; otherwise, low toxicity unless vehicle is a petroleum distillate

Irritated skin and mucous membranes, skin vesicles, nausea, vomiting, bloody diarrhea, burning pain in back and urethra, respiratory depression, seizures, coma, abortion, menorrhagia

Irritability, CNS excitation, muscle spasms, atonia, tonic-clonic seizures, respiratory failure, pulmonary edema, nausea, vomiting, obtundation, coma

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Airway protection; consideration of alkalinization for QRS widening; admission of patients who have symptoms > 6 hours after ingestion

Stage 1:Stage 2: Symptom-free 8 hours to several daysStage 3: Nausea, vomiting, diarrhea, liver enlargement, jaundice, hemorrhages, kidney damage, seizures, comaToxicity enhanced by alcohol, fats, or digestible oils

Milk, starch, or flour po; early airway support; fluid and electrolytes; treatment of shock; early, aggressive airway management

Tachycardia, headache, drowsiness, hypotension, coma, rapid severe acidosis, seizures, death, possibly bitter almond odor on breath, bright red venous blood

Burning pain in mouth and esophagus, brown-stained mucous membranes, laryngeal edema, vomiting, abdominal pain, diarrhea, shock, nephritis, circulatory collapse

See specific gas, eg, Ammonia gas, Carbon monoxide , Chlorine (tear gas), Hydrogen sulfide (sewer gas, volatile hydrides), and Organophosphates (nerve gas)

Observation for myocardial or pulmonary disorder (usually before emergency department arrival)For hyperthermia, external cooling

Anticholinergic symptoms (eg, tachycardia, hyperthermia, mydriasis, warm and dry skin, urinary retention, ileus, delirium)

Because major problems result from aspiration and not GI absorption, gastric evacuation usually not warrantedSupportive care for pulmonary edema, oxygen, respiratory support

Violent myoclonus that simulates generalized seizures but with intact mental status, caused by minor stimuli; complete muscle relaxation between apparent seizures; perspiration; respiratory arrest

Stained lips (white, brown, then black), argyria (slate gray or blue skin discoloration), gastroenteritis, shock, vertigo, seizures

Ingestion: Blood transfusion for severe hemolysis, urine alkalinization for hemoglobinuria, benzodiazepines to control seizures

Ingestion: Observation for kidney and liver damage; respiratory, cardiac, and circulatory supportInhalation: Respiratory, cardiac, and circulatory support

Supportive care, IV glucose, correction of dehydration and electrolyte abnormalitiesFor gastritis, IV H2 blockers or proton pump inhibitors

Flushing of eyes for 15 minutes with tap water or salineIf severe toxicity, positive pressure oxygen to manage pulmonary edema, respiratory support

Tachycardia, headache, drowsiness, hypotension, coma, rapid severe acidosis, seizures, death, possibly bitter almond odor on breath, bright red venous bloodVery rapidly lethal (in 1–15 minutes)

Excitement, confusion, muscular twitching, weakness, abdominal cramps, generalized myoclonus, CNS depression, rapid respirations, palpitations, cardiovascular collapse, coma, respiratory failure

Lethargy, nystagmus, pinpoint pupils, tachycardia, coma, respiratory depression (NOTE: Toxicity may be delayed up to 12 hours.)

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Ingestion: Severe gastric cramps, vomiting, diarrhea, dry throat, cough, dyspnea, headache, shock, coma, brown urine, renal failure

Delayed onset of symptoms with nitrogen oxides unless heavy concentrationFatigue, cough, dyspnea, pulmonary edemaLater, bronchitis, pneumonia

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Dizziness, weakness, headache, euphoria, nausea, vomiting, ventricular arrhythmia, paralysis, seizuresWith chronic poisoning, aplastic anemia, hypokalemia, leukemia, CNS depressionIrritability, CNS excitation, muscle spasms, atonia, tonic-clonic seizures, respiratory failure, pulmonary edema, nausea, vomiting, obtundation, coma

Nitrogen oxides (see also Chlorine, Fluorides, Hydrogen sulfide, Sulfur dioxide; and Environmental Pulmonary Disease)Air contaminants that form atmospheric oxidants and that have been liberated from missile fuels, explosives, or agricultural wastesCobaltous chlorideHydrogen chlorideHydrogen fluoride

Anticholinergic symptoms (eg, tachycardia, hyperthermia, mydriasis, warm and dry skin, urinary retention, ileus, delirium)

See specific components (eg, Barium compounds, Fluorides, Phosphorus [yellow or white], Thallium salts, Anticoagulants, warfarins)

Methemoglobinemia, cyanosis, anoxia, GI disturbance, vomiting, headache, dizziness, hypotension, respiratory failure, coma

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Ingestion: As for inhalation, except for direct pulmonary effectInhalation: Bronchial irritation, pneumonia (pulmonary congestion and edema, decreased respiration, dyspnea), drunkenness, stupor, ketosis, cardiac arrhythmias

Decontamination with water, avoidance of vomiting and aspiration, oxygen, respiratory support, ECG monitoring (ventricular fibrillation can occur early)For severe anemia, blood transfusionsReplacement of potassium as necessary

Guidelines for Chelation Therapy)Maintenance of fluid and electrolyte balance, hemodialysis for renal failure, observation for GI perforationSkin contact: Soap and water for scrubbing

Chlorinated and other halogenated hydrocarbons (in many insecticides)AldrinBenzene hexachlorideChlordaneChlorothalonilDDD (2-dichlorethane)DDT (chlorophenothane)DicofolDieldrinDienochlorDilanEndosulfanEndrinHeptachlorMethoxychlorPerchlordeconeProlanToxapheneOther chlorinated organic insecticides and industrial compounds

Tachycardia, tachypnea and hypoxia after inhalation, skin and mucous membrane irritation, glomerulonephritis, hypothyroidism (rare)

Severe toxicity with 60–250 mL (2–8 ounces) in adults or 8–10 mL (2 teaspoons) in childrenLatency period 12–18 hoursHeadache, weakness, leg cramps, vertigo, seizures, retinal injury, dimmed vision, metabolic acidosis, decreased respiration

Possibly sedation, seizures, QRS prolongation, sympathomimetic symptoms (eg, tremor, mydriasis, tachycardia, hypertension, diaphoresis), hypotension

Cyanosis due to formation of methemoglobin and sulfhemoglobin, dyspnea, weakness, vertigo, angina, rashes and urticaria, vomiting, delirium, depression, respiratory and circulatory failure

Commonly, sedation, vomiting, tremor, tachycardiaPossibly, seizures, hallucinations, hypotension, serotonin syndromeRarely, death

Respiratory support, treatment of seizures, maintenance of fluid balance, avoidance of all oils derived from cantharides

Sympathomimetic toxidromes, headache, nausea, dystonia, hallucinations, nystagmus, fasciculations, diarrhea, seizures, agitation, muscle rigidity

lacrimation and burning eyes, cough, dyspnea, pulmonary edema, caustic skin burns, erythema, pain, profuse salivation, nausea, vomiting, diarrhea, confusion, vertigo, sudden collapse, unconsciousness

Agitation, sinus tachycardia, seizures, comaWithdrawal syndrome similar to withdrawal symptoms after stopping gamma-hydroxybutyrate (GHB)

Symptomatic hyperammonemia: L-Carnitine 100 mg/kg (6 g maximum) IV over 30 minutes with maintenance dose of 15 mg/kg every 4 hours

Tachycardia, tachypnea and hypoxia after inhalation, skin and mucous membrane irritation, glomerulonephritis, hypothyroidism (rare)

Possibly sedation, seizures, QRS prolongation, sympathomimetic symptoms (eg, tremor, mydriasis, tachycardia, hypertension, diaphoresis), hypotensionRarely death

Later, carpopedal spasm, lumbar pain, oxalate crystalluria, oliguria progressing to anuria and acute renal failure, respiratory distress, seizures, coma

* Inclusion of one poison with another (eg, toluene with benzene) in a single row indicates that the terms are synonymous, that the poisons are chemically related, or that one poison is an ingredient or impurity of the other. Lists of substances containing the poison are examples and are not all-inclusive. Most drugs are included as members of a class (eg, beta blockers) and only the most common and important drugs will have a separate row entry.

Respiratory and cardiovascular supportive measures, monitoring of liver functionSymptomatic hyperammonemia: L-Carnitine 100 mg/kg (6 g maximum) IV over 30 minutes with maintenance dose of 15 mg/kg every 4 hours Asymptomatic hyperammonemia: L-Carnitine 100 mg/kg orally every 6 hours (3 g/day maximum)

lacrimation and burning eyes, cough, dyspnea, pulmonary edema, caustic skin burns, erythema, pain, profuse salivation, nausea, vomiting, diarrhea, confusion, vertigo, sudden collapse, unconsciousness

Guidelines for Chelation Therapy), electrolyte and fluid balance, respiratory support, monitoring of GI tract, treatment of shock, control of seizures, monitoring for liver and renal failure

Burning pain in mouth and esophagus, brown-stained mucous membranes, laryngeal edema, vomiting, abdominal pain, diarrhea, shock, nephritis, circulatory collapse

Decontamination with water, avoidance of vomiting and aspiration, oxygen, respiratory support, ECG monitoring (ventricular fibrillation can occur early)

Slightly to highly toxic effects; similar to those of organophosphates except cholinesterase inhibition is not permanent

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Ingestion: Abdominal cramps, nausea, vomiting, headache, confusion, dysuria, intravascular hemolysis, seizures, hemolytic anemia in people with G6PD deficiency

Guidelines for Chelation Therapy), electrolyte and fluid balance, respiratory support, monitoring of GI tract, treatment of shock, control of seizures, monitoring for liver and renal failure

Airway protection; consideration of alkalinization for QRS widening; admission of patients who have symptoms > 6 hours after ingestionFor severe symptoms, consideration of IV lipid emulsion

Ingestion:Skin contact: Washing with copious soap and waterInhalation: Flushing of eyes with saline, oxygen, respiratory support

Nonspecific and highly variable symptoms, which are often delayed 6–24 hoursSympathomimetic toxidromes, headache, nausea, dystonia, hallucinations, nystagmus, fasciculations, diarrhea, seizures, agitation, muscle rigidityHypotension and bradycardia (which may be ominous)

Nausea, vomiting, confusion, bradycardia, hypotension, total cardiovascular collapseToxicity sometimes occurring after hyperglycemia

A wide range of effects (eg, sedation, seizures, excitement, coma, dystonia, hypotension, tachycardia, ventricular arrhythmias or torsades de pointes, anticholinergic effects, hyperthermia, agranulocytosis, or hypothermia)

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Single ingestion—typically not seriousWith multiple ingestions, coagulopathy with increased PT/INRHigher risk of coagulopathy with single dose of superwarfarins

Fatigue, thirst, flushing, nausea, vomiting, abdominal pain, hyperpyrexia, tachycardia, loss of consciousness, dyspnea, respiratory arrest, skin absorption

Allergic response (including anaphylactic reactions and skin sensitivity) in sensitive people; otherwise, low toxicity unless vehicle is a petroleum distillate

Stained lips (white, brown, then black), argyria (slate gray or blue skin discoloration), gastroenteritis, shock, vertigo, seizures

Restlessness; hyperacuity of hearing, vision, and tactile sensationViolent myoclonus that simulates generalized seizures but with intact mental status, caused by minor stimuli; complete muscle relaxation between apparent seizures; perspiration; respiratory arrest

Wakefulness, restlessness, anorexia, vomiting, dehydration, seizures, tachycardiaIn adults, greater toxicity after acute overdose added to chronic intake

Extrapyramidal symptoms (eg, ataxia, muscular and carpopedal spasms, torticollis), usually idiosyncraticWith overdose, dry mouth, drowsiness, seizures, coma, respiratory depression

Nausea, vomiting, abdominal pain, headache, confusion, visual disturbances, CNS depression, ventricular fibrillation, kidney injury, liver injury, cirrhosis

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Irritability, CNS excitation, muscle spasms, atonia, tonic-clonic seizures, respiratory failure, pulmonary edema, nausea, vomiting, obtundation, coma

Removal from skin, prevention or treatment of electrolyte abnormalities and shock, control of seizuresFor severe poisoning (rare), dialysis

Nausea, vomiting, abdominal pain, headache, confusion, visual disturbances, CNS depression, ventricular fibrillation, kidney injury, liver injury, cirrhosis

Ingestion: Oral and gastric pain, nausea, vomiting, hematemesis, shock, hematuria, anuria, coma, respiratory failureSkin contact: Irritation, coagulation necrosis (with high concentrations), dermatitis, hypersensitivityInhalation: Eye, nose, and respiratory tract irritation; laryngeal spasm and edema; dysphagia; bronchitis; pneumonia

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Thirst, diarrhea, vomiting, light-headedness, burning feet, increased heart rate and BP, cardiovascular collapse, seizures, hypotension, coma, abortion, gangrene of feet, cataracts

Fatigue, thirst, flushing, nausea, vomiting, abdominal pain, hyperpyrexia, tachycardia, loss of consciousness, dyspnea, respiratory arrest, skin absorption

Variable toxicity depending on length of exposure, concentration inhaled, and respiratory and circulatory ratesVarious symptoms depending on % carboxyhemoglobin in bloodHeadache, vertigo, vomiting, dyspnea, confusion, dilated pupils, seizures, coma

Inhalation: Bronchial irritation, pneumonia (pulmonary congestion and edema, decreased respiration, dyspnea), drunkenness, stupor, ketosis, cardiac arrhythmias

Respiratory support, treatment of seizures, maintenance of fluid balance, avoidance of all oils derived from cantharidesNo specific antidote

Acute ingestion: Thirst, burning abdominal pain, vomiting, diarrhea; CNS symptoms (eg, irritability, inattentiveness, decreased level of consciousness, seizures)

CyanidesBitter almond oil (artificial and natural)Hydrocyanic acidPotassium cyanidePrussic acidSodium cyanideWild cherry syrup

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Ingestion: Severe gastric cramps, vomiting, diarrhea, dry throat, cough, dyspnea, headache, shock, coma, brown urine, renal failureInhalation: Pneumonitis with dyspnea and bilateral pulmonary infiltrates, hypoxia, death

BP = blood pressure; BSA = body surface area; CNS = central nervous system; ECG = electrocardiogram; GI = gastrointestinal; INR = international normalized ratio; NGT = nasogastric tube; NSAID = nonsteroidal anti-inflammatory drug; PT = prothrombin time; SSRI = selective serotonin reuptake inhibitor.

Inhalation: Severe respiratory and ocular irritation, glottal spasm, cough, choking, vomiting, pulmonary edema, cyanosis

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See specific agentChlorinated and other halogenated hydrocarbons, Organophosphates, Paradichlorobenzene, and Pyrethroids

Acute: Severe gastroenteritis, burning mouth pain, salivation, abdominal pain, vomiting, colitis, nephrosis, anuria, uremiaWith alkyl and phenyl mercurials, skin burnsChronic: Gingivitis, mental disturbance, neurologic deficits

Stimulation then depression, nausea, vomiting, loss of self-control, anxiety, hallucinations, sweating, hyperthermia, seizures, MI (rare)

Nausea, vomiting, diarrhea, hemorrhagic gastroenteritis, weakness, lethargy, CNS depression, seizures, “boiled lobster” rash, shock

Anticholinergic symptoms (eg, tachycardia, hyperthermia, mydriasis, warm and dry skin, urinary retention, ileus, delirium)