Improper management of discarded needles and other sharps can pose a health risk to the public and waste workers. For example, discarded needles may expose waste workers to potential needle stick injuries and potential infection when containers break open inside garbage trucks or needles are mistakenly sent to recycling facilities. Janitors and housekeepers also risk injury if loose sharps poke through plastic garbage bags. Used needles can transmit serious diseases, such as human immunodeficiency virus (HIV) and hepatitis.

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Other federal agencies have regulations regarding medical waste. These agencies include Centers for Disease Control (CDC), Occupational Safety and Health Administration (OSHA), U.S. Food and Drug Administration (FDA), and potentially others.

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After the MWTA expired in 1991, states largely took on the role of regulating medical waste under the guidance developed from the two year program.

Concern for the potential health hazards of medical wastes grew in the 1980s after medical wastes were washing up on several east coast beaches. This prompted Congress to enact The MWTA of 1988. The MWTA was a two-year federal program in which EPA was required to promulgate regulations on management of medical waste. The Agency did so on March 24, 1989. The regulations for this two year program went into effect on June 24, 1989 in four states - New York, New Jersey, Connecticut, and Rhode Island and Puerto Rico. The regulations expired on June 21, 1991.

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Most states have since further developed their own programs resulting in each state program differing significantly from each other.

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Medical waste is primarily regulated by state environmental and health departments. EPA has not had authority, specifically for medical waste, since the Medical Waste Tracking Act (MWTA) of 1988 expired in 1991. It is important to contact your state environmental program first when disposing of medical waste. Contact your state environmental protection agency and your state health agency for more information regarding your state's regulations on medical waste.

With EPA's tighter HMIWI standards, the number of HMIWIs in the United States has declined since 1997. This has lead to an increase in the use of alternative technologies for treating medical waste. The alternative treatments are generally used to render the medical waste non-infectious then the waste can be disposed of as solid waste in landfills or incinerators. Many states have regulations requiring medical waste treatment technologies to be certified, licensed or regulated. Check with your state for additional regulation regarding treatment of medical waste.

RCRA regulations do not define wastes as hazardous due to their infectious nature, including those contaminated by the novel coronavirus which causes COVID-19. EPA has, however, established air emission standards for solid waste incinerators that treat “Hospital/Medical/Infectious” wastes.

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Medical waste is a subset of wastes generated at health care facilities, such as hospitals, physicians' offices, dental practices, blood banks, and veterinary hospitals/clinics, as well as medical research facilities and laboratories. Generally, medical waste is healthcare waste that that may be contaminated by blood, body fluids or other potentially infectious materials and is often referred to as regulated medical waste.

For historical information regarding EPA’s work under the Medical Waste Tracking Act of 1989 including several draft studies related to medical waste management, please search EPA’s archive using the term "medical waste."

RCRA creates the framework for the proper management of hazardous and non-hazardous solid waste. While medical waste and infectious waste are non-hazardous solid waste under RCRA, they are subject to state waste regulatory programs. State programs can vary. The Healthcare Environmental Resource Center provides a map that links to state regulated medical waste resources.

EPA concluded from the information gathered during this period that the disease-causing potential of medical waste is greatest at the point of generation and naturally tapers off after that point. Thus, risk to the general public of disease caused by exposure to medical waste is likely to be much lower than risk for the healthcare workers.

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More than 90 percent of potentially infectious medical waste was incinerated before 1997. In August of 1997, EPA promulgated regulations creating stringent emission standards for medical waste incinerators due to significant concerns over detrimental air quality affecting human health. EPA’s Office of Air Quality Planning and Standards continues to review and revise the Hospital Medical Infectious Waste Incinerator (HMIWI) standards as required most recently in May of 2013.

Hazardous Storage signs are essential to any safety program to prevent injuries, fires, and unhealthful conditions. Chemicals and dangerous substances must be stored in a way that minimizes the risks and limits people's exposure to them.Western Safety Sign designs and manufactures hazardous storage signage, and is available in a variety of materials depending where you are using the sign, and can be customized to convey your specific safety message.

EPA has jurisdiction over medical waste treatment technologies, which claim to reduce the infectiousness of the waste (i.e. that claim any antimicrobial activity) by using chemicals. This jurisdiction comes from the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA). Companies wishing to make such claims must register their product under FIFRA through EPA's Office of Prevention, Pesticide, and Toxic Substances (OPPTS), Antimicrobial Division.