Ultra short pulse laser

Standard optical mirrors, may not be the optimal option for lasers. Standard coatings will induce interference effects that will be harmful to ultrashort pulses. Alpine Research Optics designed a comprehensive set specially for practical applications.

Substrate analogs that bind to active sites of enzymes to form product of covalent bond that is stable on binding site to inhibit chemical reaction; irreversible enzyme inhibitor that react with functional group of enzyme and has more specificity for enzyme.

Ultrafast opticswiki

Ultrafast optics provide unique gain flattened, minimal GDD, and low scatter. E-max coatings are our most popular product because it is optimized for peak pulse damage resistance. ARO is a trusted supplier of LaserNetUS.

In addition to these stock components, ARO can readily produce optics customized in virtually every aspect including size, shape, substrate material, surface specifications, and performance characteristics. Please contact our technical sales department to discuss your custom optics requirements.

Ultrafastlaser applications

Close cooperation between ARO thin film engineers and leading ultrafast researchers has enabled us to develop high performance mirrors and polarizers for the ultrafast industry. The E-max coating was designed by ARO engineers to provide high laser damage thresholds for Ti:Sapphire lasers. Our products are built to withstand ns, ps, or fs pulse durations for your ultrafast laser system.

Affinity label or reactive substrate analog are molecules that have a similar structure to the substrate allowing them to covalently bind to the active site of the enzyme. They react with the substrate, inhibiting the enzyme. Essentially, affinity labels mimic the functional properties of the substrate, but consequently irreversibly inhibits the enzyme through the strong covalent bonding. Because of its similarity to the substrate, it initially binds at the active site; however, the covalent bonds it forms irreversibly modify the enzyme. They are much more specific than group specific inhibitors. They are usually highly reactive. Also, there will be alkylate nucleophilic amino acids in the enzyme. However, their properties are rather non-selective and toxic, making them not as useful in many situations.

ARO offers thin film polarizers that have been designed to provide the top performance in Ti:Sapphire amplifiers. Multiple round trips in the amplifier have a multiplying effect on the characteristics of any optic in the cavity. ARO sales team can get you up to speed with the latest technology and offer a free quote.

Ultrafastlaser Physics

Ultrafast OpticsPDF

Standard optical mirrors, may not be the optimal option for ultrafast applications. Standard coatings will induce interference effects that will be harmful to ultrashort pulses.

Affinity labelling can be used to localize a given site within a protein of a known amino acid sequence. It allows comparisons to be made between the substrate sites of the enzyme in the solution and the sites localized within the crystalline form through X-ray diffraction. This can test whether the compound that is bound irreversibly at the substrate site can influence the enzyme conformation, subunit interaction, or the reactivity of other ligand sites.

Tosyl phenylalanyl chloromethyl ketone is a substrate analog for chymotrypsin. This molecules binds at the active site and then react irreversibly with histidine residue at that site, inhibiting the enzyme. File:800px-Tosyl phenylalanyl chloromethyl ketone.PNG

ARO’s ultrafast mirrors are designed to deliver superior performance for demanding beam steering tasks in Ti:Sapphire laser applications. Currently, we deliver an optimal combination of high reflectivity, broad spectral bandwidth, excellent laser damage resistance, and minimal group delay dispersion. ARO supplies two standard series of ultrafast laser mirrors. Our E-Max high reflectors are specifically optimized to attain the highest pulse Energy damage threshold, while our B-Max coatings are optimized to deliver the Broadest possible bandwidth.