The superior signal-to-noise of the NSPARC detector allows super-resolution imaging with minimal photodamage – great for live samples.

Confocal and multiphoton systems with a large field of view enable high throughput imaging of 3D model systems for drug discovery research.

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Two-photon microscopy

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by F Hempel · 2021 · Cited by 11 — Broadband coherent anti-Stokes Raman scattering (B-CARS) has emerged in recent years as a promising chemosensitive high-speed imaging ...

Deep tissue two-photon microscopy

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To achieve this, you would use a larger aperture (smaller f-number), such as f/1.8 or f/2.8, for a shallow depth of field. This allows more light to reach the ...

Multiphotonmicroscopy

Fast resonant scanning and spinning disk systems combine with deep learning-based denoising for better signal-to-noise with less photodamage.

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Confocal and multiphoton microscopes continue to set the standard for deep imaging and in thick model organisms and tissues.

Spinning disk systems from CrestOptics are flexible and budget-friendly choices for a variety of applications. The large 25 mm field of view is a great match for high throughput imaging. The optional DeepSIM module provides super-resolution via multi-spot structured illumination.

Spinning disk confocal systems from Yokogawa Life Sciences provide fast and user-friendly options for live cell, organoid, and other imaging applications. The CSU-W1 SoRa spinning disk system provides super-resolution using Optical Pixel Reassignment (OPR) technology.

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Spinning disk confocal systems from Yokogawa Life Sciences provide fast and user-friendly options for live cell, organoid, and other imaging applications. The CSU-W1 SoRa spinning disk system provides super-resolution using Optical Pixel Reassignment (OPR) technology.

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Nikon’s latest confocal microscope, leveraging deep learning-based AI tools to simplify acquisition and improve image quality. Fast scanning combined with a large 25 mm field of view enables high throughput imaging with unmatched edge-to-edge image quality. Super-resolution provided by the NSPARC detector.

Patch clamp electrophysiology is complemented by deep imaging in live brain tissue using confocal and multiphoton systems.

Nikon’s latest confocal microscope, leveraging deep learning-based AI tools to simplify acquisition and improve image quality. Fast scanning combined with a large 25 mm field of view enables high throughput imaging with unmatched edge-to-edge image quality. Super-resolution provided by the NSPARC detector.

The newest multiphoton microscope from Nikon is a top choice for deep imaging. The next generation 2K resonant scanner captures fast in vivo dynamics with high resolution over a large field of view. The AX R MP also supports confocal imaging with visible wavelengths and super-resolution using the NSPARC detector.

Achieves super-resolution and deep imaging while realizing low-noise images in deep observation via the NSPARC detector.

Inverting Band Pass Filter Circuit ... This type of band pass filter is designed to have a much narrower pass band. The centre frequency and bandwidth of the ...

The newest multiphoton microscope from Nikon is a top choice for deep imaging. The next generation 2K resonant scanner captures fast in vivo dynamics with high resolution over a large field of view. The AX R MP also supports confocal imaging with visible wavelengths and super-resolution using the NSPARC detector.

Realizes high wavelength selectivity with near-infrared excitation, making it ideal for live-cell long-wavelength imaging.

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Microscopyu

Spinning disk systems from CrestOptics are flexible and budget-friendly choices for a variety of applications. The large 25 mm field of view is a great match for high throughput imaging. The optional DeepSIM module provides super-resolution via multi-spot structured illumination.

Image scanning microscopy (ISM) is a super-resolution technique that takes advantage of structured detection of each point in a point-scanning system to improve both resolution and signal-to-noise (S/N), a great choice for low light imaging. Both the AX / AX R confocal and AX R MP multiphoton systems may be equipped with the Nikon Spatial Array Confocal (NSPARC) detector for ISM imaging.

Product Family Description Simplify Component Selection for SZ61 and SZX7 Microscopes Systems Ready to use with Camera of your Choice Boom Stand Systems In…

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Imaging of 3D cell cultures using Nikon’s confocal/multiphoton systems is well supported by their inherent optical sectioning capabilities.

Equipped with an NSPARC detector for super-resolution, achieving exceptionally low-noise and high-spatial-resolution imaging.

Confocal microscopy provides optical sectioning, the ability to observe discrete planes in 3D samples, by using one or more apertures to block out-of-focus light. Nikon offers both point-scanning confocal instruments, led by our AX / AX R confocal system, as well as spinning disk (field scanning) confocal systems from top manufacturers.

Multiphoton microscopy is preferred for deep imaging applications in thick specimens, including intravital imaging. Non-linear excitation restricts fluorescence to the laser focus and near-infrared illumination minimizes absorption and scattering. Nikon offers the AX R MP multiphoton system, available with microscope stand options optimized for large specimens.