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7 days ago — Lens, in optics, piece of glass or other transparent substance that is used to form an image of an object by focusing rays of light from the ...

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RGB beam combiners enable any two or three primary colours in the visible wavelength region to be combined. Combiners are available for either 2 or 3 ...

Page contents: Historic (1995) Giant Fresnel Lens Page; FAQ (including where you can get your giant fresnel lens!) The New Lens ...

by HH Nasse · Cited by 21 — In a second part we will show you a number of illustrating images. Page 3. Carl Zeiss. Camera Lens Division. 3. Point Spread Function.

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2024621 — A microscope objective lens produces a real, magnified image of an object placed within the field of view.

a Institute of Pharmaceutical Science, School of Biomedical Sciences, King's College London, London, UK

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Glycosyltransferases (GTs) are a large family of carbohydrate-active enzymes, which act as nature's glycosylation agents. GTs catalyse the transfer of a mono- or oligosaccharide from a glycosyl donor to an individual acceptor, and play a central role in the biosynthesis of complex carbohydrates, glycans and glycoconjugates. Several GTs have emerged as potential drug targets in a range of therapeutic areas, including infection, inflammation and cancer. Small molecular GT inhibitors are therefore sought after not only as chemical tools for glycobiology, but also as potential lead compounds for drug discovery. Most existing GT inhibitors are donor or acceptor analogues with limited potential for further development due to intrinsic drawbacks, such as a lack of cell penetration and limited chemical stability. In this article, we review recent progress in the identification of alternative inhibitor chemotypes that are not structurally derived from GT donors or acceptors. This growing class of non-substrate-like GT inhibitors now includes several examples with drug-like properties, which provide exciting new starting points for medicinal chemistry and drug discovery. The increasing availability of such alternative GT inhibitor chemotypes represents a significant advance, which will help realise the considerable potential of this important enzyme family as therapeutic targets.

Aug 1, 2019 — You may have used a UV light to detect urine spills in carpets, upholstery and flooring. But why does urine glow like that?

b Department of Chemistry, School of Natural & Mathematical Sciences, King's College London, Britannia House, 7 Trinity Street, London, UK E-mail: gerd.wagner@kcl.ac.uk Tel: +44 (0)20 7848 1926