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Vision loss can have many causes, some of which are temporary. This article looks at the causes and treatments associated with vision loss in more…
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“These are highly conserved energy sources in cells — they are the cells’ batteries. The light increases the charge of the mitochondria and allows them to increase their energy output that has declined with age or disease.”
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By way of example, he noted that red light has been shown to be neuroprotective in a monkey model of Parkinson’s disease.
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One likely reason is that mitochondria follow the body’s circadian rhythm, and as Prof. Jeffery said of them, “They are probably busy doing other things in the afternoon.”
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The study showed that a 3-minute exposure to deep red light in the morning once per week can improve vision that has declined due to aging, for up to 1 week.
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The small study cohort of females and males ranged in age from 34 to 70 years. The researchers measured improvements in the participants’ vision by scoring their color contrast vision, or the ability to differentiate between colors. All the participants had normal color contrast vision at the start of the trial.
Prof. Jeffery said the vision improvement that the study found results from the fact that “the lights we use influence mitochondria.” He explained their importance:
The color contrast vision of the participants who were exposed to red light in the morning improved by an average of 17%.
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Some individuals were exposed to 3 minutes of deep red light in the morning, and others in the afternoon. The red light was roughly one camera stop brighter, or about twice as bright as the overall lighting in the testing area.
“To give a wider context,” said Prof. Jeffery, “we are also working on bees, because some of the critically important insecticides, the neonicotinoids, work by damaging mitochondria and killing bees. We have used almost identical technology to protect them.”
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“The great thing about the retina is that it has more mitochondria than any other organ, because it uses so much energy. On top of this, you have easy optical access — you can direct light right onto retinal mitochondria, which you can’t do to mitochondria in the liver or the kidney. Add to this the fact that the retina ages faster than any other organ, and you can simply test its function by asking people what they see, and you have a perfect target for red light therapy.”
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The study also revealed that 3 minutes is the optimal length for light exposure and that the vision improvement lasts up to 1 week.
A study from researchers at University College London in the United Kingdom found that a brief application of the right kind of light can improve declining vision.
Three minutes is as effective as a 45-minute exposure, “but use [it] for hours, and it does not work,” said Prof. Jeffery.
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Temporomandibular joint (TMJ) disorders may cause vision problems. Learn about the causes, symptoms, treatment options, and more.
“Mitochondria rule so many aspects of our lives, and we need a way to improve their health, particularly in aging. Red light use is now being applied in a large number of labs and also in clinical trials. It will likely provide us with a very simple and economic way of doing this with wide applicability.”
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Eyesight declines after the age of 40 years and is linked with a 70% reduction in ATP, which means that the cells lack energy to function properly.
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Another possibility has to do with energy requirements unique to early daytime. “Maybe it’s all about getting up in the morning and being ready to do things,” Prof. Jeffery speculated. “This draws energy that needs replacing. No matter what you do, [mitochondria] do not respond the rest of the day or at night.”
The researchers began their investigation with flies and mice, before work with the study’s human participants began. Lead author Prof. Glen Jeffery told Medical News Today, “It does not really matter what the animal is or, to some extent, what the cell is, the light will impact.”
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