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Emission signal from this volume is collected by a CCD camera positioned perpendicular to this plane – imaging the entire XY dimension as you would in a traditional epifluorescence microscope. The result is an optical section that is slightly thicker than a typical confocal section, but can be imaged at a much faster rate.

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LightSheet microscopy is a fluorescence technique that projects a thin ‘sheet’ of excitation light perpendicular to the direction of observation. This type of a system uses cylindrical optics to focus a laser into a narrow field in the Z dimension, thus illuminating the entire XY image plane but only a small volume in the focus (or Z) dimension.

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Once you are seen in the clinic, you can remain a patient with us. You do not have to be transferred to another clinic for primary care services. However, the resident providing care will change as residents graduate from the program and new residents enter.

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The LightSheet microscope can be used for imaging entire embryos, brain and other organs from a variety of small animal models. It is a great way to get large volumes of 3D data quickly over a very large field of view.

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Internal medicine is the diagnosis, treatment, and care of adults across the health spectrum. At Northern Arizona Healthcare Medical Group – Cottonwood, a teaching clinic operated by residents, we see you quickly and treat you with expertise.

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Our clinic is ideal for patients who have recently been discharged from Verde Valley Medical Center, as well as those who do not have a primary care provider.  We can address your needs, whether simple or complex, at our convenient location in VVMC’s outpatient department.

Perhaps most importantly, the sample holder can be translated in 4 dimensions (XYZ, 360° Rotation) which allows the user to position the sample for optimal sectioning. A typical confocal only moves in X, Y and Z. The ability of the stage to rotate allows optical sectioning from multiple angles through the specimen. This is very valuable for large scale whole mounts where more traditional imaging from only one angle would be limited by the working distance of the microscope objective, typically a few millimeters. With a system like this you can image a few millimeters from opposite slides of the sample thus doubling the effective sectioning volume.