LightGuide, Inc. uses proprietary software and high-powered projector systems to guide and confirm the completion of complex tasks, from assembly to quality control and training. The technology provides visualization, traceability, and flexibility in manufacturing and assembly processes.

LightguideOptics

“We are honored to have G2 join our existing investment team of Capital Midwest Fund and Michigan Capital Advisors to further advance this goal. Together, we will help more industrial manufacturers benefit from digital transformation that simplifies complex work and provides greater operational excellence.”

Light guide LED

“LightGuide is bridging the gap between Industry 4.0 technology and the best of human intelligence, expanding and empowering the worldwide manufacturing workforce,” says Paul Ryznar, founder and CEO of LightGuide.

LightGuidecost

LightGuide Inc., a leading projected augmented reality (AR) software platform that improves manual assembly and manufacturing processes for companies worldwide, has raised a $15M Series B financing led by G2 Venture Partners, with continued participation from Capital Midwest Fund and Michigan Capital Advisors.

Overview: This is a commerically-produced clone of the Betzig system described in Science October 2014 and currently running at the HHMI Janelia Campus's Advanced Imaging Center. It is designed for low-light 3D time lapse imaging. This is NOT like the Zeiss Lightsheet.Z1 meant for large preps! Imaging is by means of water-immersion objectives and is limited to less than 100 micrometers depth of penetration. All samples MUST be on 5mm round coverslips. Please be sure to arrange all sessions in advance with Core Staff as use of this microscope requires careful calibration of the system before each use.

Light guide design

LightGuide’s patented Industry 4.0 technology standardizes and improves manual assembly processes by projecting virtual step-by-step instructions onto an employee’s work surface. The visual and intuitive light guidance provides immersive, “No Faults Forward” process control through defect prevention and traceable analytics. The system helps ensure processes are completed safely, correctly, and efficiently.

Light guide meaning

Overview: The Zeiss Lightsheet Z.1 is one of the first commercially available Single Plane Illumination microscopes. It is particularly suited for temperature controlled, long-term imaging of living samples such as zebrafish or Drosophila embryos. Samples can be kept in the chamber and imaged for hours or days. Sensitive cameras and single plane illumination allow for gentle sample illumination, reducing photodamage.

​This microscope is no longer available through the Integrated Microscopy Core.  As of April 2022 it is housed and managed by the Organismal Biology and Anatomy CDIF Facility.

LightGuidesystems

LightGuide works with a variety of leading automotive, aerospace, heavy equipment, agricultural equipment producers, and distribution companies, as well as in the health care field, to solve a growing variety of challenges. Key clients include GE, Bosch, Caterpillar, Magna, and JR Automation.

What is SPIM? Selective / Single Plane Illumination Microscopy is particularly suited to long-term timelapse imaging of larger living specimens, such as zebrafish, Drosophilia embryos, and small plants. This technology has also been used to image living and fixed 3D cell cultures, including organoids, cysts and 3D cell migration assays.

Overview: The LaVision Ultramicroscope is an upright lightsheet microscope ideal for large, fixed and cleared fluorescent samples. For comparisons of clearing techniques, Visikol has a nice chart detailing the basics of many commmon methods.

The investment will combine G2’s focus on investing in the digitization of industrial markets with LightGuide’s AR software platform to further accelerate LightGuide’s growth. Core initiatives for the company include expansion of its global sales and support network to meet growing demand for AR work instructions and continued R&D in its cloud infrastructure and software suite.