Advanced LightSource

The ALM is a core facility of the national research infrastructure PPBI-Portuguese Platform of BioImaging and of the European research infrastructure Euro-Bioimaging ERIC.

Phone: +351 226 074 900 Email: info@i3s.up.pt Address: Rua Alfredo Allen, 208 4200-135 Porto, Portugal

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The scientific platform provides scientific advice on experimental design, training in the practical use of the equipment and image analysis, and scientific advice on the development of research projects. It also aims to increase knowledge in bioimaging by organising several post-graduate courses in light microscopy and image analysis for the scientific and industrial communities.

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Advanced Light Microscopy (ALM) is the i3S scientific platform specialising in state-of-the-art optical microscopy for the study of cellular systems in life science research areas such as cell biology, oncobiology, neurobiology, immunology, and biomaterials. The ALM provides open access to high-end imaging technology and extensive expertise in advanced optical microscopy applied to multi-dimensional imaging of cells and tissues, live cell imaging, functional and molecular imaging (e.g. FRAP, FRET, FLIM), and bio-image data analysis. Available equipment includes transmission/widefield fluorescence microscopes (one with TIRF), spinning disc microscopes (one with SR-SIM), laser scanning confocal microscopes (one with STED, FLIM, and FCS), and a light sheet microscope. Workstations with bio-image analysis software are also available.

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