I have been using a pE-4000 for optogenetic experiments using in vitro slices for just over a year now. The pE-4000 has been fantastic for my needs: the ability to simultaneously use multiple wavelengths of light has allowed me to carry out experiments using two different opsins to study how external inputs converge on hippocampal interneurons. I’m currently setting up my own research group at the University of Exeter, and all of my patch-clamp rigs will have a pE-4000 on them, as they are such versatile devices for optogenetic experiments.

We are happy with the pe-400max as it’s super-compact, bright and quiet! I forgot that it was turned on. Also, no more changing expensive and environmentally hazardous mercury bulbs. We look forward to some nice imaging days ahead

We needed an easy to install, triggerable, intensity-modulated light source. An LED is by far the easiest and cheapest solution. Furthermore, small latencies between triggered light pulses are crucial for the analysis of the kinetics of measurements. We used the CoolLED pE-300ultra, which meets these requirements. Another great advantage of this product lies in its versatility for use in upcoming experiments covering different wavelengths. Its flexibility allows the performance of very complex experimental protocols.

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At CoolLED we are committed to giving our customers outstanding service right from the start and throughout the lifetime of the product. Please get in touch if you have any questions or would like a quote. You can also browse our site for technical resources and general support.

Did you know that LED illumination systems help laboratories reduce their carbon footprint, protecting laboratory staff along the way?

For manufacturers who wish to gain a competitive advantage through bright, stable and controllable illumination, CoolLED’s world-renowned LED technology is available in customised configurations.

We are extremely happy with our CoolLED pE-300white System. Integration with our microscope was simple, and the robust system has never needed maintenance or alignment. I am particularly happy with the user interface as it is simple and intuitive.

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We chose the CoolLED light source with our live cell imaging system because we need a fluorescence light source that is efficient, easy to use and has a very bright and robust signal for fluorescence – but is also incredibly gentle on cell samples. Our system is designed around a lack of phototoxicity, so when using fluorescence with holotomography, we really need the ideal excitation that keeps cells happy, but shows exactly what is labelled.

CoolLED light sources are user-friendly, offering versatile control options and delivering bright illumination across a broad spectrum of wavelengths.

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Learn how CoolLED Illumination Systems are driving advanced research applications across the globe with app notes, videos, research papers and more.

The Cy5 (635 nm) LED in the pE-400 Series is a game changer and they also offer massively improved YFP excitation too. They are fantastic products!

The Techno LED-Backlit Flat Panel Luminaire is a great energy-saving solution featuring a 0-10V dimmable driver and AC100-277 input voltage. This luminaire reduces energy consumption up to 60% and includes a high-quality isolated driver and flicker-free performance. Installation is easy with recessed, suspending, and surface-mounted options and it complies with UL and DLC certifications. Plus, the optional photocell sensor provides added convenience.

The pE-300white has been a great asset for a core facility. It has meant less time spent changing bulbs (so less downtime to the user and more productive time for ourselves) and no longer worrying about users turning the light source on and off throughout the day as multiple users come and go.  The controllable intensity has also proved highly popular with users who are now able to set the minimum light level required to scan their samples and minimise the risk of phototoxic damage and bleaching to their specimens

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There is no warm up/cool down which makes things easier for all users. I look forward to reduced maintenance with the long lifespan of the LEDs and no bulb replacements.  No complaints really! I would definitely recommend the system to others as superior to standard mercury lamp illumination.

This LED Backlit flat panel luminaire is the perfect solution to reducing energy consumption with its 0-10V dimmable driver, AC100-277 input voltage, and CRI over 80. This reduces energy consumption up to 60% and comes with a high-quality isolated driver and a flicker-free performance. Installation is easy with our recessed, suspending, and surface-mounted options. Plus, it complies with UL and DLC certifications and offers the option of a photocell sensor for added convenience. Upgrade your lighting today with the Techno LED-Backlit Flat Panel Luminaire!

My team told me that the pE-800fura is a very good light source – powerful and suitable for multi-purpose applications. The same for our academic collaborators who clearly saw the difference compared to their aging light source.

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CoolLED designs and manufactures cutting edge LED Illumination Systems for researchers and clinicians using the latest LED technology.

The company has specialised in fluorescence microscopy since it introduced the first commercially available LED Illumination System in 2006. LED microscope lighting is now the method of choice because these systems are more stable, longer lasting, and energy efficient than traditional mercury based illuminators as well as offering superior safety and environmental features.

Thank you all for your helpful support, prompt assistance and good communication – and also patience and understanding as we dealt with some administrative delays on our side.  I wish all companies had a support team as good to deal with as CoolLED!

See our range of LED Illumination Systems for fluorescence and transmitted illumination applications, select the desired light delivery method and find your ideal system.

Overall, I found it very easy to install and operate. The intensity of illumination is great and I like that it is highly adjustable.

Controls Dimming High quality isolated driver; 0-10V dimming; Flicker free. Motion Sensor and Emergency battery available. 50,000 lifetime hours.

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Toxic mercury-based microscope illuminators are bad news for the environment, draw a lot of power and have a short lifetime.

LED illumination systems are cleaner, have a long lifetime and use less power. Our pE-300 Series is also ACT label certified and is a natural choice for labs who want to play their part in helping the environment.

Customers are our focus and we pride ourselves in assisting them in an efficient and friendly manner no matter if it is a product enquiry, price request or fault report.

The customer service at CoolLED is phenomenal! Justyna was amazing with product feedback. I have NO hesitation recommending coolLED for their products and service. Simply fantastic!

Applications: 1.- Office and school lightning: office room, meeting room, classroom, etc. 2.- Commercial lighting: shopping malls, supermarkets, retail shops, etc. 3.- Special Lighting: hospital, laboratory, dust-free workshops.

All our lab members have been very glad that the microscope representative recommended CoolLED pE-300white to us. It is really cool! With this new and award-winning technology, we got rid of the big and heavy fluorescence power supply box and camera controller, and will never worry about the life time of a fluorescence lamp again, because we can use the pE-300white almost forever. Now we can turn the fluorescence on or off instantly and adjust the intensity precisely and conveniently with no shutters required. In addition, the illumination is clean, bright and stable across the spectrum, and it is not just safer for us but also energy-efficient for our environment. We love it! Thank you, CoolLED!